Hemimethylation and hypersensitivity are early events in transcriptional reactivation of human inactive X-linked genes in a hamster x human somatic cell hybrid.
Reactivation of the hypoxanthine phosphoribosyltransferase (HPRT) gene on an inactive human X chromosome in a somatic cell hybrid was analyzed following exposure to 5-aza-2'-deoxycytidine. Hemimethylation and chromatin hypersensitivity in the 5' CpG island appeared by 6 h after exposure and continue...
Salvato in:
| Pubblicato in: | Mol Cell Biol |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
1992
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360251/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1380647/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.9.3819-3826.1992 |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|