Rab3D Is Critical for Secretory Granule Maturation in PC12 Cells

Neuropeptide- and hormone-containing secretory granules (SGs) are synthesized at the trans-Golgi network (TGN) as immature secretory granules (ISGs) and complete their maturation in the F-actin-rich cell cortex. This maturation process is characterized by acidification-dependent processing of cargo...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Kögel, Tanja, Rudolf, Rüdiger, Hodneland, Erlend, Copier, John, Regazzi, Romano, Tooze, Sharon A., Gerdes, Hans-Hermann
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602456/
https://ncbi.nlm.nih.gov/pubmed/23526941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057321
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