A Hydrophobic Gold Surface Triggers Misfolding and Aggregation of the Amyloidogenic Josephin Domain in Monomeric Form, While Leaving the Oligomers Unaffected

Protein misfolding and aggregation in intracellular and extracellular spaces is regarded as a main marker of the presence of degenerative disorders such as amyloidoses. To elucidate the mechanisms of protein misfolding, the interaction of proteins with inorganic surfaces is of particular relevance,...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Apicella, Alessandra, Soncini, Monica, Deriu, Marco Agostino, Natalello, Antonino, Bonanomi, Marcella, Dellasega, David, Tortora, Paolo, Regonesi, Maria Elena, Casari, Carlo Spartaco
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602447/
https://ncbi.nlm.nih.gov/pubmed/23527026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058794
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker