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ANTI-IL-6 ANTIBODY TREATMENT BUT NOT IL-6 KNOCKOUT IMPROVES INTESTINAL BARRIER FUNCTION AND REDUCES INFLAMMATION FOLLOWING BINGE ETHANOL EXPOSURE AND BURN INJURY

IL-6 is an inflammatory cytokine known to be elevated in chronic diseases and following insults such as trauma and infection. While necessary for the development of B cells and Th17 cells, IL-6, at elevated levels, can also cause tissue damage and lead to a rise in inflammation. Previous work in our...

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Detalhes bibliográficos
Main Authors: Zahs, Anita, Bird, Melanie D., Ramirez, Luis, Choudhry, Mashkoor A., Kovacs, Elizabeth J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602394/
https://ncbi.nlm.nih.gov/pubmed/23376955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e318289d6c6
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