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Decreased Pulmonary Inflammation Following Ethanol and Burn Injury in Mice Deficient in TLR4 but not TLR2 Signaling

BACKGROUND: Clinical and laboratory evidence suggests that alcohol consumption prior to burn injury leads to dysregulated immune function and subsequent higher rates of morbidity and mortality. Our laboratory previously observed higher levels of pro-inflammatory cytokines and leukocyte infiltration...

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Autors principals: Bird, Melanie D., Zahs, Anita, Deburghgraeve, Cory, Ramirez, Luis, Choudhry, Mashkoor A., Kovacs, Elizabeth J.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063502/
https://ncbi.nlm.nih.gov/pubmed/20608903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2010.01260.x
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