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Steady-State NTPase Activity of Dengue Virus NS3: Number of Catalytic Sites, Nucleotide Specificity and Activation by ssRNA

Dengue virus nonstructural protein 3 (NS3) unwinds double stranded RNA driven by the free energy derived from the hydrolysis of nucleoside triphosphates. This paper presents the first systematic and quantitative characterization of the steady-state NTPase activity of DENV NS3 and their interaction w...

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Main Authors: Incicco, J. Jeremías, Gebhard, Leopoldo G., González-Lebrero, Rodolfo M., Gamarnik, Andrea V., Kaufman, Sergio B.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602377/
https://ncbi.nlm.nih.gov/pubmed/23526990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058508
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