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Steady-State NTPase Activity of Dengue Virus NS3: Number of Catalytic Sites, Nucleotide Specificity and Activation by ssRNA
Dengue virus nonstructural protein 3 (NS3) unwinds double stranded RNA driven by the free energy derived from the hydrolysis of nucleoside triphosphates. This paper presents the first systematic and quantitative characterization of the steady-state NTPase activity of DENV NS3 and their interaction w...
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Main Authors: | , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
Public Library of Science
2013
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3602377/ https://ncbi.nlm.nih.gov/pubmed/23526990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058508 |
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