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The Extent of Synaptic Stripping of Motoneurons after Axotomy Is Not Correlated to Activation of Surrounding Glia or Downregulation of Postsynaptic Adhesion Molecules

Synapse elimination in the adult central nervous system can be modelled by axotomy of spinal motoneurons which triggers removal of synapses from the cell surface of lesioned motoneurons by processes that remain elusive. Proposed candidate mechanisms are removal of synapses by reactive microglia and...

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Autori principali: Berg, Alexander, Zelano, Johan, Thams, Sebastian, Cullheim, Staffan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602371/
https://ncbi.nlm.nih.gov/pubmed/23527240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059647
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