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CHFR protein expression predicts outcomes to taxane-based first line therapy in metastatic NSCLC

PURPOSE: Currently, there is no clinically validated test for the prediction of response to tubulin-targeting agents in non-small cell lung cancer (NSCLC). Here, we investigated the significance of nuclear expression of the mitotic checkpoint gene checkpoint with forkhead and ringfinger domains (CHF...

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Détails bibliographiques
Auteurs principaux: Pillai, Rathi N, Brodie, Seth A, Sica, Gabriel L, Shaojin, You, Li, Ge, Nickleach, Dana C, Yuan, Liu, Varma, Vijay A, Bonta, Dacian, Herman, James G, Brock, Malcom V, Ribeiro, Maria JA, Ramalingam, Suresh S, Owonikoko, Taofeek K, Khuri, Fadlo R, Brandes, Johann C
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602233/
https://ncbi.nlm.nih.gov/pubmed/23386692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-2995
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