Suppression of c-Src activity by C-terminal Src kinase involves the c-Src SH2 and SH3 domains: analysis with Saccharomyces cerevisiae.

The kinase activity of c-Src is normally repressed in vertebrate cells by extensive phosphorylation of Y-527. C-terminal Src kinase (CSK) is a candidate for the enzyme that catalyzes this phosphorylation. We have used budding yeast to study the regulation of c-Src activity by CSK in intact cells. Ex...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Main Authors: Murphy, S M, Bergman, M, Morgan, D O
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360223/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7689149/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.9.5290
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