ROSIGLITAZONE TREATMENT DOES NOT DECREASE AMYLOID DEPOSITION IN TRANSPLANTED ISLETS FROM TRANSGENIC MICE EXPRESSING HUMAN ISLET AMYLOID POLYPEPTIDE

In human islet transplantation, insulin independence decreases over time. We previously showed that amyloid deposition following transplantation of islets from human islet amyloid polypeptide (hIAPP) transgenic mice resulted in β-cell loss, and that rosiglitazone treatment decreased islet amyloid de...

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Hauptverfasser: Udayasankar, Jayalakshmi, Zraika, Sakeneh, Aston-Mourney, Kathryn, Subramanian, Shoba L, Brooks-Worrell, Barbara M, Taborsky, Gerald J, Hull, Rebecca L
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602214/
https://ncbi.nlm.nih.gov/pubmed/23267797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.transproceed.2012.05.079
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