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Therapeutic Inhibition of the Alternative Complement Pathway Attenuates Chronic EAE
Previous studies from our laboratory using complement-mutant mice demonstrated that the alternative pathway is the dominant activation pathway responsible for complement-mediated pathology in demyelinating disease. Using a well-characterized inhibitory monoclonal antibody (mAb 1379) directed against...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3602149/ https://ncbi.nlm.nih.gov/pubmed/23337717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2012.12.018 |
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