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Complement alternative pathway activation in the autologous phase of nephrotoxic serum nephritis

The complement cascade is an important part of the innate immune system, but pathological activation of this system causes tissue injury in several autoimmune and inflammatory diseases, including immune complex glomerulonephritis. We examined whether mice with targeted deletion of the gene for facto...

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Detalhes bibliográficos
Main Authors: Thurman, Joshua M., Tchepeleva, Svetlana N., Haas, Mark, Panzer, Sarah, Boackle, Susan A., Glogowska, Magdalena J., Quigg, Richard J., Holers, V. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378099/
https://ncbi.nlm.nih.gov/pubmed/22492944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00422.2011
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