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Complement alternative pathway activation in the autologous phase of nephrotoxic serum nephritis

The complement cascade is an important part of the innate immune system, but pathological activation of this system causes tissue injury in several autoimmune and inflammatory diseases, including immune complex glomerulonephritis. We examined whether mice with targeted deletion of the gene for facto...

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Bibliografski detalji
Glavni autori: Thurman, Joshua M., Tchepeleva, Svetlana N., Haas, Mark, Panzer, Sarah, Boackle, Susan A., Glogowska, Magdalena J., Quigg, Richard J., Holers, V. Michael
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378099/
https://ncbi.nlm.nih.gov/pubmed/22492944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00422.2011
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