CLINICAL SIGNIFICANCE OF CD33 NON-SYNONYMOUS SINGLE NUCLEOTIDE POLYMORPHISMS (SNPs) IN PEDIATRIC PATIENTS WITH ACUTE MYELOID LEUKEMIA TREATED WITH GEMTUZUMAB-OZOGAMICIN-CONTAINING CHEMOTHERAPY

PURPOSE: Purpose of this study was to evaluate clinical implications of CD33 SNPs in pediatric acute myeloid leukemia (AML) patients treated with gemtuzumab ozogamicin (GO) based therapy. EXPERIMENTAL DESIGN: We genotyped four CD33 SNPs: rs35112940 (G>A; Arg304Gly), rs12459419 (C>T; Ala14Val),...

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Main Authors: Mortland, Leslie, Alonzo, Todd A, Walter, Roland B, Gerbing, Robert B, Mitra, AK, Pollard, Jessica A, Loken, Michael R, Hirsch, Betsy, Raimondi, Susana, Franklin, Janet, Pounds, Stanley, Cao, Xueyuan, Rubnitz, Jeffrey E, Ribeiro, Raul C, Gamis, Alan, Meshinchi, Soheil, Lamba, Jatinder K
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602123/
https://ncbi.nlm.nih.gov/pubmed/23444229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-3115
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