The blockade of NMDA receptor ion channels by ketamine is enhanced in developing rat cortical neurons

Ketamine is a non-competitive antagonist of NMDA receptors (NMDARs) commonly used as a dissociative anesthetic in many pediatric procedures. Ketamine acts primarily by blocking NMDA ligand-gated channels. Experimental studies indicate that ketamine administration used for inducing clinically relevan...

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Main Authors: Jin, Jianhui, Gong, Kerui, Zou, Xiaoju, Wang, Ruirui, Lin, Qing, Chen, Jun
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602117/
https://ncbi.nlm.nih.gov/pubmed/23395831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2013.01.034
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