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Human Coding Synonymous Single Nucleotide Polymorphisms at Ramp Regions of mRNA Translation

According to the ramp model of mRNA translation, the first 50 codons favor rare codons and have slower speed of translation. This study aims to detect translational selection on coding synonymous single nucleotide polymorphisms (sSNP) to support the ramp theory. We investigated fourfold degenerate s...

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Bibliografiske detaljer
Main Authors: Li, Quan, Qu, Hui-Qi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602041/
https://ncbi.nlm.nih.gov/pubmed/23527255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059706
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