Dominant positive and negative selection using a hygromycin phosphotransferase-thymidine kinase fusion gene.

The hygromycin phosphotransferase gene was fused in-frame with the herpes simplex virus type 1 thymidine kinase gene. The resulting fusion gene (termed HyTK) confers hygromycin B resistance for dominant positive selection and ganciclovir sensitivity for negative selection and provides a means by whi...

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Hlavní autoři: Lupton, S D, Brunton, L L, Kalberg, V A, Overell, R W
Médium: Artigo
Jazyk:Inglês
Vydáno: 1991
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC360192/
https://ncbi.nlm.nih.gov/pubmed/1645450
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