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Dominant positive and negative selection using a hygromycin phosphotransferase-thymidine kinase fusion gene.
The hygromycin phosphotransferase gene was fused in-frame with the herpes simplex virus type 1 thymidine kinase gene. The resulting fusion gene (termed HyTK) confers hygromycin B resistance for dominant positive selection and ganciclovir sensitivity for negative selection and provides a means by whi...
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| Publicado no: | Mol Cell Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360192/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1645450/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.6.3374 |
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