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Sensing cellular stress through STIM proteins

In response to decreasing Ca(2+) levels in the endoplasmic reticulum, STIM proteins couple with Orai channels in the plasma membrane, leading to Ca(2+) influx into the cell. In addition to Ca(2+)-related endoplasmic reticulum stress, STIM proteins are emerging as general stress sensors that react to...

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Bibliografiska uppgifter
Huvudupphovsmän: Soboloff, Jonathan, Madesh, Muniswamy, Gill, Donald L
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601892/
https://ncbi.nlm.nih.gov/pubmed/21769090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.619
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