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The structures of three metabolites of the algal hepatotoxin okadaic acid produced by oxidation with human cytochrome P450
Four metabolites of okadaic acid were generated by incubation with human recombinant cytochrome P450 3A4. The structures of two of the four metabolites have been determined by MS/MS experiments and 1D and 2D NMR methods using 94 and 133 μg of each metabolite. The structure of a third metabolite was...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3601775/ https://ncbi.nlm.nih.gov/pubmed/22608922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2012.04.046 |
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