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Prodrug Strategy for PSMA-targeted Delivery of TGX-221 to Prostate Cancer Cells
TGX-221 is a potent, selective, and cell membrane permeable inhibitor of the PI3K p110β catalytic subunit. Recent studies showed that TGX-221 has anti-proliferative activity against PTEN-deficient tumor cell lines including prostate cancers. The objective of this study was to develop an encapsulatio...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3601665/ https://ncbi.nlm.nih.gov/pubmed/22494444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp3000309 |
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