Thymidylate Synthase and Folyl-polyglutamate synthase (FPGS) Are Not Clinically Useful Markers of Response to Pemetrexed [Pem] in Patients with Malignant Pleural Mesothelioma [MPM]

PURPOSE: Thymidylate synthase (TS) is a potential predictor of outcome after pemetrexed (Pem) in patients with malignant pleural mesothelioma (MPM), and assays measuring TS levels are commercially marketed. The goal of this study was to further evaluate the value of TS and to study another potential...

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Detalhes bibliográficos
Main Authors: Schwed Lustgarten, Daniel E., Deshpande, Charuhas, Aggarwal, Charu, Wang, Liang-Chuan, Saloura, Vassiliki, Vachani, Anil, Wang, Li-Ping, Litzky, Leslie, Feldman, Michael, Creaney, Jeanette, Nowak, Anna K., Langer, Corey, Inghilleri, Simona, Stella, Giulia, Albelda, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601580/
https://ncbi.nlm.nih.gov/pubmed/23486267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e318283da3e
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