Enhancer-binding activity of the tal-1 oncoprotein in association with the E47/E12 helix-loop-helix proteins.

Almost 30% of patients with T-cell acute lymphoblastic leukemia (T-ALL) bear structural alterations of tal-1, a presumptive proto-oncogene that encodes sequences homologous to the helix-loop-helix (HLH) DNA-binding and dimerization domain. Analysis of the tal-1 gene product reveals that its HLH doma...

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Publicado en:	Mol Cell Biol
Autores principales:	Hsu, H L, Cheng, J T, Chen, Q, Baer, R
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis 1991
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360139/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2038315/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.6.3037-3042.1991
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