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Dose-dependent effects on cell proliferation, seminiferous tubules, and male germ cells in the fetal rat testis following exposure to di (n-butyl) phthalate

Adult male rats gestationally exposed to di(n-butyl)phthalate (DBP) have dysgenetic testes characterized by seminiferous epithelial degeneration, clustering of Leydig cells, and decreased spermatogenesis. Cell proliferation and apoptosis are key processes regulating development of the testis, and al...

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Autores principales: Boekelheide, Kim, Kleymenova, Elena, Liu, Kejun, Swanson, Cynthia, Gaido, Kevin W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601329/
https://ncbi.nlm.nih.gov/pubmed/19165735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jemt.20684
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