Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins.

E6-AP is a 100-kDa cellular protein that mediates the interaction of the human papillomavirus type 16 and 18 E6 proteins with p53. The association of p53 with E6 and E6-AP promotes the specific ubiquitination and subsequent proteolytic degradation of p53 in vitro. We recently isolated a cDNA encodin...

Ful tanımlama

Detaylı Bibliyografya

Yayımlandı:	Mol Cell Biol
Asıl Yazarlar:	Huibregtse, J M, Scheffner, M, Howley, P M
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Taylor & Francis 1993
Konular:	Research Article
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360130/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8393140/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.8.4918-4927.1993
Etiketler:	Etiketle Etiket eklenmemiş, İlk siz ekleyin!