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Strong emerging rationale for combining oncogene-targeted agents with immunotherapy
In a mastocytoma model expressing mutant c-KIT, a combination of the c-KIT inhibitor dasatinib and an OX40-specific monoclonal antibody synergized in triggering a strong antitumor T-cell response that promoted curative therapeutic effects. Along with a number of other recent studies, these data supp...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Landes Bioscience
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3601155/ https://ncbi.nlm.nih.gov/pubmed/23524978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.22730 |
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