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Non-contact helium-based plasma for delivery of DNA vaccines: Enhancement of humoral and cellular immune responses

Non-viral in vivo administration of plasmid DNA for vaccines and immunotherapeutics has been hampered by inefficient delivery. Methods to enhance delivery such as in vivo electroporation (EP) have demonstrated effectiveness in circumventing this difficulty. However, the contact-dependent nature of E...

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Detalhes bibliográficos
Main Authors: Connolly, Richard J., Chapman, Taryn, Hoff, Andrew M., Kutzler, Michele A., Jaroszeski, Mark J., Ugen, Kenneth E.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601149/
https://ncbi.nlm.nih.gov/pubmed/22894954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.21624
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