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Enhancement of antigen specific humoral immune responses after delivery of a DNA plasmid based vaccine through a contact-independent helium plasma

Non-viral in vivo delivery of DNA, encoding for specific proteins, has traditionally relied on chemical or physical forces applied directly to tissues. Physical methods typically involve contact between an applicator/electrode and tissue and often results in transient subject discomfort. To overcome...

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Bibliografische gegevens
Hoofdauteurs: Connolly, Richard J., Rey, Jose I., Lambert, Vance M., Wegerif, Garrett, Jaroszeski, Mark J., Ugen, Kenneth E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156891/
https://ncbi.nlm.nih.gov/pubmed/21195804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.12.054
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