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Spontaneous Detachment of the Leading Head Contributes to Myosin VI Backward Steps

Myosin VI is an ATP driven molecular motor that normally takes forward and processive steps on actin filaments, but also on occasion stochastic backward steps. While a number of models have attempted to explain the backwards steps, none offer an acceptable mechanism for their existence. We therefore...

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Autors principals: Ikezaki, Keigo, Komori, Tomotaka, Yanagida, Toshio
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601099/
https://ncbi.nlm.nih.gov/pubmed/23527046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058912
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