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Direct Transformation of Lung Microenvironment by Interferon-α Treatment Counteracts Growth of Lung Metastasis of Hepatocellular Carcinoma

BACKGROUND: Interferon (IFN)-α is effective in inhibiting tumor growth and metastasis of hepatocellular carcinoma (HCC). However, the biologic mechanisms of IFN-α treatment in lung metastasis are not yet clear. METHODS: The effect of IFN-α treatment was studied by using an orthotopic xenograft model...

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Autori principali: Zhuang, Peng-Yuan, Shen, Jun, Zhu, Xiao-Dong, Zhang, Ju-Bo, Tang, Zhao-You, Qin, Lun-Xiu, Sun, Hui-Chuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601095/
https://ncbi.nlm.nih.gov/pubmed/23527047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058913
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