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IL-1R1 is required for dendritic cell–mediated T cell reactivation within the CNS during West Nile virus encephalitis

Infections of the central nervous system (CNS) with cytopathic viruses require efficient T cell responses to promote viral clearance, limit immunopathology, and enhance survival. We found that IL-1R1 is critical for effector T cell reactivation and limits inflammation within the CNS during murine We...

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Detalhes bibliográficos
Main Authors: Durrant, Douglas M., Robinette, Michelle L., Klein, Robyn S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600909/
https://ncbi.nlm.nih.gov/pubmed/23460727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20121897
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