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The Sequence Dependence of Cell Growth Inhibition by EGFR-Tyrosine Kinase Inhibitor ZD1839, Docetaxel and Cisplatin in Head and Neck Cancer

BACKGROUND: This study was to explore whether the efficacy of the EGFR tyrosine kinase inhibitor ZD1839 (Z, Iressa, gefitinib) plus chemotherapeutic agents docetaxel (D) and cisplatin (P) may benefit from sequencing of the combination. METHODS: Three head and neck cancer cell lines were used to stud...

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書誌詳細
主要な著者: Klass, Carmen M., Choe, Mi Sun, Hurwitz, Selwyn J., Tighiouart, Mourad, Zhang, Xin, Chen, Zhuo (Georgia), Shin, Dong M.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600558/
https://ncbi.nlm.nih.gov/pubmed/19399750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hed.21103
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