The Sequence Dependence of Cell Growth Inhibition by EGFR-Tyrosine Kinase Inhibitor ZD1839, Docetaxel and Cisplatin in Head and Neck Cancer

BACKGROUND: This study was to explore whether the efficacy of the EGFR tyrosine kinase inhibitor ZD1839 (Z, Iressa, gefitinib) plus chemotherapeutic agents docetaxel (D) and cisplatin (P) may benefit from sequencing of the combination. METHODS: Three head and neck cancer cell lines were used to stud...

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Main Authors: Klass, Carmen M., Choe, Mi Sun, Hurwitz, Selwyn J., Tighiouart, Mourad, Zhang, Xin, Chen, Zhuo (Georgia), Shin, Dong M.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600558/
https://ncbi.nlm.nih.gov/pubmed/19399750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hed.21103
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