A carregar...
Free energy landscape for the binding process of Huperzine A to acetylcholinesterase
Drug-target residence time (t = 1/k(off), where k(off) is the dissociation rate constant) has become an important index in discovering better- or best-in-class drugs. However, little effort has been dedicated to developing computational methods that can accurately predict this kinetic parameter or r...
Na minha lista:
| Main Authors: | , , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3600462/ https://ncbi.nlm.nih.gov/pubmed/23440190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301814110 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|