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Probing the folding free energy landscape of the src-SH3 protein domain
The mechanism and thermodynamics of folding of the Src homology 3 (SH3) protein domain are characterized at an atomic level through molecular dynamics with importance sampling. This methodology enables the construction of the folding free energy landscape of the protein as a function of representati...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC138565/ https://ncbi.nlm.nih.gov/pubmed/12446834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.242293099 |
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