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Probing the folding free energy landscape of the src-SH3 protein domain

The mechanism and thermodynamics of folding of the Src homology 3 (SH3) protein domain are characterized at an atomic level through molecular dynamics with importance sampling. This methodology enables the construction of the folding free energy landscape of the protein as a function of representati...

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Detaylı Bibliyografya
Asıl Yazarlar: Shea, Joan-Emma, Onuchic, José N., Brooks, Charles L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2002
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC138565/
https://ncbi.nlm.nih.gov/pubmed/12446834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.242293099
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