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Biosynthesis of ionotropic acetylcholine receptors requires the evolutionarily conserved ER membrane complex
The number of nicotinic acetylcholine receptors (AChRs) present in the plasma membrane of muscle and neuronal cells is limited by the assembly of individual subunits into mature pentameric receptors. This process is usually inefficient, and a large number of the synthesized subunits are degraded by...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3600456/ https://ncbi.nlm.nih.gov/pubmed/23431131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216154110 |
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