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Biosynthesis of ionotropic acetylcholine receptors requires the evolutionarily conserved ER membrane complex

The number of nicotinic acetylcholine receptors (AChRs) present in the plasma membrane of muscle and neuronal cells is limited by the assembly of individual subunits into mature pentameric receptors. This process is usually inefficient, and a large number of the synthesized subunits are degraded by...

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Autors principals: Richard, Magali, Boulin, Thomas, Robert, Valérie J. P., Richmond, Janet E., Bessereau, Jean-Louis
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600456/
https://ncbi.nlm.nih.gov/pubmed/23431131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216154110
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