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Eight genes are required for functional reconstitution of the Caenorhabditis elegans levamisole-sensitive acetylcholine receptor

Levamisole-sensitive acetylcholine receptors (L-AChRs) are ligand-gated ion channels that mediate excitatory neurotransmission at the neuromuscular junctions of nematodes. They constitute a major drug target for anthelminthic treatments because they can be activated by nematode-specific cholinergic...

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Detalhes bibliográficos
Main Authors: Boulin, Thomas, Gielen, Marc, Richmond, Janet E., Williams, Daniel C., Paoletti, Pierre, Bessereau, Jean-Louis
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587545/
https://ncbi.nlm.nih.gov/pubmed/19020092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806933105
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