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TLR9 is Actively Recruited to Aspergillus fumigatus Phagosomes and Requires the N-terminal Proteolytic Cleavage Domain for Proper Intracellular Trafficking()
Toll-like receptor 9 (TLR9) recognizes unmethylated CpG DNA and induces innate immune responses. TLR9 activation is a multistep process requiring proteolytic cleavage and trafficking to endolysosomal compartments for ligand-induced signaling. However, the rules that govern the dynamic subcellular tr...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3600358/ https://ncbi.nlm.nih.gov/pubmed/21059889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002760 |
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