Decreased expression of ADAMTS-1 in human breast tumors stimulates migration and invasion

BACKGROUND: ADAMTS-1 (a disintegrin and metalloprotease with thrombospondin motifs) is a member of the ADAMTS family of metalloproteases. Here, we investigated mRNA and protein levels of ADAMTS-1 in normal and neoplastic tissues using qPCR, immunohistochemistry and immunoblot analyses, and we addres...

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Autores principales: Freitas, Vanessa M, do Amaral, Jônatas Bussador, Silva, Thaiomara A, Santos, Emerson S, Mangone, Flávia R, Pinheiro, João de Jesus, Jaeger, Ruy G, Nagai, Maria A, Machado-Santelli, Gláucia Maria
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600045/
https://ncbi.nlm.nih.gov/pubmed/23289900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-2
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