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A Covalently Stabilized lipid-polycation-DNA (sLPD) Vector for Antisense Oligonucleotide Delivery
Antisense oligonucleotide G3139 is designed for Bcl-2 downregulation and is known to induce toll-like receptor activation. Novel stabilized lipid-polycation-DNA (sLPD) nanoparticles were constructed and evaluated for the delivery of G3139 to human carcinoma KB cells and for bioactivity in vivo. Poly...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3599967/ https://ncbi.nlm.nih.gov/pubmed/21366344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp100272k |
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