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Novel indole-bearing combretastatin analogues as tubulin polymerization inhibitors

BACKGROUND: The combretastatins are a class of natural stilbenoids. These molecules generally share three common structural features: a trimethoxy "A"-ring, a "B"-ring containing substituent often at C3′ and C4′, and an ethene bridge between the two rings, which provides necessar...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kumar, Sunil, Mehndiratta, Samir, Nepali, Kunal, Gupta, Manish K, Koul, Surrinder, Sharma, Parduman R, Saxena, Ajit K, Dhar, Kanaya L
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3599526/
https://ncbi.nlm.nih.gov/pubmed/23452433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2191-2858-3-3
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