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Targeting and killing of glioblastoma with activated T cells armed with bispecific antibodies
BACKGROUND: Since most glioblastomas express both wild-type EGFR and EGFRvIII as well as HER2/neu, they are excellent targets for activated T cells (ATC) armed with bispecific antibodies (BiAbs) that target EGFR and HER2. METHODS: ATC were generated from PBMC activated for 14 days with anti-CD3 mono...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3599512/ https://ncbi.nlm.nih.gov/pubmed/23433400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-83 |
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