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Age-dependent roles of peroxisomes in the hippocampus of a transgenic mouse model of Alzheimer’s disease

BACKGROUND: Alzheimer’s Disease (AD) is a progressive neurodegenerative disease, especially affecting the hippocampus. Impairment of cognitive and memory functions is associated with amyloid β-peptide-induced oxidative stress and alterations in lipid metabolism. In this scenario, the dual role of pe...

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Bibliographic Details
Main Authors: Fanelli, Francesca, Sepe, Sara, D’Amelio, Marcello, Bernardi, Cinzia, Cristiano, Loredana, Cimini, AnnaMaria, Cecconi, Francesco, Ceru', Maria Paola, Moreno, Sandra
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3599312/
https://ncbi.nlm.nih.gov/pubmed/23374228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-8-8
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