Single-chain immunotoxins directed at the human transferrin receptor containing Pseudomonas exotoxin A or diphtheria toxin: anti-TFR(Fv)-PE40 and DT388-anti-TFR(Fv).

Two single-chain immunotoxins directed at the human transferrin receptor have been constructed by using polymerase chain reaction-based methods. Anti-TFR(Fv)-PE40 is encoded by a gene fusion between the DNA sequence encoding the antigen-binding portion (Fv) of a monoclonal antibody directed at the h...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Batra, J K, Fitzgerald, D J, Chaudhary, V K, Pastan, I
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1991
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359914/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2005905/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.4.2200-2205.1991
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