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Osbpl8 Deficiency in Mouse Causes an Elevation of High-Density Lipoproteins and Gender-Specific Alterations of Lipid Metabolism
OSBP-related protein 8 (ORP8) encoded by Osbpl8 is an endoplasmic reticulum sterol sensor implicated in cellular lipid metabolism. We generated an Osbpl8(−/−) (KO) C57Bl/6 mouse strain. Wild-type and Osbpl8KO animals at the age of 13-weeks were fed for 5 weeks either chow or high-fat diet, and their...
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Κύριοι συγγραφείς: | , , , , , , , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
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Public Library of Science
2013
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3598917/ https://ncbi.nlm.nih.gov/pubmed/23554939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058856 |
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