PREDIVAC: CD4+ T-cell epitope prediction for vaccine design that covers 95% of HLA class II DR protein diversity

BACKGROUND: CD4+ T-cell epitopes play a crucial role in eliciting vigorous protective immune responses during peptide (epitope)-based vaccination. The prediction of these epitopes focuses on the peptide binding process by MHC class II proteins. The ability to account for MHC class II polymorphism is...

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Main Authors: Oyarzún, Patricio, Ellis, Jonathan J, Bodén, Mikael, Kobe, Boštjan
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598884/
https://ncbi.nlm.nih.gov/pubmed/23409948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-52
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