Point mutations upstream of the yeast ADH2 poly(A) site significantly reduce the efficiency of 3'-end formation.

The sequences directing formation of mRNA 3' ends in Saccharomyces cerevisiae are not well defined. This is in contrast to the situation in higher eukaryotes in which the sequence AAUAAA is known to be crucial to proper 3'-end formation. The AAUAAA hexanucleotide is found upstream of the poly(A) sit...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Hyman, L E, Seiler, S H, Whoriskey, J, Moore, C L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359886/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2005893/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.4.2004-2012.1991
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