Point mutations upstream of the yeast ADH2 poly(A) site significantly reduce the efficiency of 3'-end formation.

The sequences directing formation of mRNA 3' ends in Saccharomyces cerevisiae are not well defined. This is in contrast to the situation in higher eukaryotes in which the sequence AAUAAA is known to be crucial to proper 3'-end formation. The AAUAAA hexanucleotide is found upstream of the poly(A) sit...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Hyman, L E, Seiler, S H, Whoriskey, J, Moore, C L
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1991
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359886/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2005893/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.4.2004-2012.1991
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