Age-Dependent Neuroplasticity Mechanisms in Alzheimer Tg2576 Mice Following Modulation of Brain Amyloid-β Levels

The objective of this study was to investigate the effects of modulating brain amyloid-β (Aβ) levels at different stages of amyloid pathology on synaptic function, inflammatory cell changes and hippocampal neurogenesis, i.e. processes perturbed in Alzheimer’s disease (AD). Young (4- to 6-month-old)...

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Main Authors: Lilja, Anna M., Röjdner, Jennie, Mustafiz, Tamanna, Thomé, Carina M., Storelli, Elisa, Gonzalez, Daniel, Unger-Lithner, Christina, Greig, Nigel H., Nordberg, Agneta, Marutle, Amelia
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598857/
https://ncbi.nlm.nih.gov/pubmed/23554921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058752
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